Neuropeptide Y Recombinant Antibody [PSH16-52] - Guinea pig IgG2 (Chimeric)

Function

Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. It is secreted alongside other neurotransmitters such as GABA and glutamate. In the autonomic system it is produced mainly by neurons of the sympathetic nervous system and serves as a strong vasoconstrictor and also causes growth of fat tissue. In the brain, it is produced in various locations including the hypothalamus, and is thought to have several functions, including: increasing food intake and storage of energy as fat, reducing anxiety and stress, reducing pain perception, affecting the circadian rhythm, reducing voluntary alcohol intake, lowering blood pressure, and controlling epileptic seizures.

Background References

1. Sánchez ML et al. Neuropeptide Y Peptide Family and Cancer: Antitumor Therapeutic Strategies. Int J Mol Sci. 2023 Jun

2. Chen Z et al. Neuropeptide Y-Mediated Gut Microbiota Alterations Aggravate Postmenopausal Osteoporosis. Adv Sci (Weinh). 2023 Nov

Subcellular Location

Secreted, Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.

UNIPROT

SwissProt: P57774 Mouse

Synonyms

C-flanking peptide of NPY antibody

CPON antibody

Neuropeptide tyrosine antibody

Neuropeptide Y precursor antibody

NPY antibody

NPY_HUMAN antibody

Pro neuropeptide Y antibody

PYY 4 antibody

PYY4 antibody

Y Neuropeptide antibody