Antibodies and Life Science Research

Antibodies can bind to an infinite number of target proteins with high specificity. In 1900, Paul Ehrlich referred to antibodies as “magic bullets”. Antibodies are used in various studies due to their unique specificity. Due to their high selectivity and specificity, they are widely used in biomedical research, mainly in therapeutics, diagnostics, and many other fields. Antibodies are used to identify unknown molecules and understand various biochemical pathways. Widely used laboratory techniques such as enzyme-linked immunosorbent assay (ELISA), radioimmunoassay (RIA), confocal microscopy, electron microscopy, Western blotting, immunohistochemistry (IHC), flow cytometry, etc., are all antibody-based. Monoclonal antibodies are used to deliver radioactive isotopes, toxins, cytokines, and other active conjugates.

Applications of Antibodies in Various Research Techniques

All kinds of cancer-related research require primary antibodies (monoclonal or polyclonal antibodies). For example, they help to understand inflammation, metastasis, proliferation signals, apoptosis, autophagy, metabolism, tumor suppressors, etc. These antibodies are also necessary for the study of stem cells such as endothelial stem cell markers (e.g., CD14, CD31, CD33). Specific recombinant epigenetic antibodies are used for epigenetic research. Primary antibodies are also used in the research of protein transport, neurogenesis, axon guidance, dendritic development, neuromuscular junctions, neurotrophins, and other neurological studies.

Monoclonal antibodies can be used to identify various cell types related to immune responses and understand the mechanisms behind such responses. In addition, monoclonal antibodies are used to study the changes of T cells and B cells during development. Due to their binding specificity, antibodies can be used in various diagnostic assays, such as infection detection, allergy identification, and measurement of hormones in blood samples. They are also used as biomarkers in the blood. One of the main advantages of monoclonal antibodies is that they can be mass-produced very cheaply. Monoclonal antibodies are currently often used as laboratory probes to reveal the pathogenesis of many diseases, whether it is cancer, Alzheimer's disease, or autoimmune diseases. Monoclonal antibodies are also crucial for the typing of organ transplant tissues and transplanted blood, so they are also used to analyze body fluids for diagnosis and monitoring of hospital infections.

Advantages of HUABIO Products in Research

Researchers face many challenges in antibody-related research, especially due to the quality issues of antibodies provided by antibody suppliers. Another problem is the lack of basic information about antibody production methods. HUABIO's antibodies are characterized by strong specificity and high stability. As an antibody manufacturer pursuing excellence, we test each new batch of antibody products, compare the latest batch with the previous ones, and use the same experimental conditions to review the consistency of activity and specificity. In addition, after 16 years of unremitting efforts, HUABIO has established an industry-leading rabbit single B antibody development technology, which includes a high-throughput recombinant protein development process. The company's catalog products include recombinant rabbit monoclonal antibodies, mouse monoclonal antibodies, rabbit polyclonal antibodies, alpaca antibodies, fluorescent direct-labeled antibodies, secondary antibodies, cytokines/proteins, ADC drug small molecule detection antibodies, Elisa Kits, etc. The product quality has been highly recognized by top scientists around the world. A team of scientists composed of multiple doctors specializes in antibody structure modification and deep processing, and has a series of technologies and processes protected by independent patents. The company has passed the ISO9001 and ISO13485 quality system certifications, which not only ensures scientific rigor but also effectively controls the project cycle and cost.