Human CA125/MUC16, C-His Tag Protein

Specification

20μg

50μg

100μg

Quota

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Catalog# HA211195

Human CA125/MUC16, C-His Tag Protein

Product Information

Product name

Human CA125/MUC16, C-His Tag Protein

Catalog No.

HA211195

Predicted molecular mass

111.5 kD

Protein construction description

A DNA sequence encoding the human CA125/MUC16 (Q8WXI7) (Met 13360-Gln 14347) was expressed with a His tag at the C-terminus.

Accession

Q8WXI7

Protein construction

CA125/MUC16 (13360-14347) His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.