Human LDLR/LDL Receptor, Tag Free Protein

Specification

20μg

50μg

100μg

Quota

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Catalog# HA211287

Human LDLR/LDL Receptor, Tag Free Protein

Product Information

Product name

Human LDLR/LDL Receptor, Tag Free Protein

Catalog No.

HA211287

Predicted molecular mass

85.6 kD

Protein construction description

A DNA sequence encoding the human LDLR/LDL Receptor protein (P01130-1) (Ala 22-Arg 788) was expressed with tag free.

Accession

P01130-1

Protein construction

LDLR/LDL Receptor (22-788)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Forms a ternary complex with PGRMC1 and TMEM97 receptors which increases LDLR-mediated LDL internalization.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.